Fenbendazole cancer is a topic currently gaining interest in the medical community. This is due to a popular cancer treatment method known as the Joe Tippens Protocol. This method involves a combination of several natural substances, including fenbendazole. Fenbendazole is an over-the-counter medication used to treat parasites and worms in animals (common brands are Pancur and Safe-Guard). It is also being used by some cancer patients as part of their therapy.
Researchers have recently reported that fenbendazole, a broad-spectrum benzimidazole antihelminthic drug with mechanisms of action that overlap with those of hypoxia-selective nitroheterocyclic cytotoxins/radiosensitizers and taxanes, exerts radiosensitizing effects in tumor cells. This activity is independent of p53 status, cell cycle stage and irradiation modality. This suggests that fenbendazole could be used in combination with other cancer drugs to improve their efficacy.
To test this hypothesis, the researchers studied EMT6 mammary tumor cells in vitro and as solid tumors in mice treated with fenbendazole and either radiation or docetaxel alone or in combination. Intensive treatments of EMT6 cells with fenbendazole in both aerobic and severe hypoxic conditions resulted in significant cytotoxicity compared to untreated controls. However, these cells were still sensitive to irradiation. Interestingly, the addition of docetaxel to these intensive fenbendazole treatment regimens did not further increase the sensitivity of these cells to radiation or docetaxel.
The investigators also tested the effect of fenbendazole on glucose metabolism and found that it inhibited the uptake of glucose into malignant cells. This finding is in agreement with the observation that the proliferation of many cancer cells is fueled by glycolysis. fenbendazole cures cancer